Commonly used oral antipsychotic drugs
All antipsychotic drugs are prescription-only medicines and should only be used under close supervision by healthcare professionals. Most of them are available in oral forms such as tablets and oral solutions.
There are two types of oral antipsychotic drugs :
- Typical (the older type of drugs): examples include Chlorpromazine, Flupenthixol, Haloperidol, Trifluoperazine, Zuclopenthixol; and
- Atypical (the newer type of drugs): examples include Amisulpride, Aripiprazole, Clozapine, Olanzapine, Paliperidone, Quetiapine
While both types of antipsychotic drugs are effective, in general, the atypical antipsychotic drugs have fewer side effects than the typical ones, such as less likely to cause muscle stiffness, restlessness and tardive dyskinesia (uncontrolled movement of the mouth, tongue, face, jaw and sometimes, other parts of the body). However, atypical antipsychotic drugs can be more likely to cause weight gain and increased risk of diabetes and heart disease. Therefore, close monitoring for patient undergoing treatment is required.